How can we respond to God when he speaks to us?
To respond to God means to believe him. Anyone who wants to believe needs a heart that is ready to listen (see 1 Kings 3:9). In many ways God seeks contact with us. In every human encounter, in every moving experience of nature, in every apparent coincidence, in every challenge, every suffering, there is a hidden message from God to us. He speaks even more clearly to us when he turns to us in his Word or in the voice of our conscience. He addresses us as friends. Therefore we, too, should respond as friends and believe him, trust him completely, learn to understand him better and better, and accept his will without reservation.
CCC section (142-149)